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Dog Probiotics: Promoting Gut Health For Your Furry Friend

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Nicoleta-Maricica MafteiNicoleta-Maricica Maftei SciProfiles Scilit Preprints.org Google Scholar 1, 2, 3, Cosmin Raducu RaileanuCosmin Raducu Raileanu SciProfiles Scilit Preprints.org Google Scholar 4, Alexia Anastasia BaltaAlexia Sci Anastasia. AmbroseLenuta Ambrose SciProfiles Scilit Preprints.org Google Scholar 4, Monica BoevMonica Boev SciProfiles Scilit Preprints.org Google Scholar 1, 3, *, Denisa Batîr MarinDenisa Batîr Marin SciProfiles Scilit Preprints.org Google Scholar Scilit Preprints.org Google Scholar Scilit Preprints 1, 3 Researchers 1, 3

Department of Morphology and Functional Sciences, Faculty of Medicine and Pharmacy, University “Dunărea de Jos”, 800010 Galati, Romania

Submitted: 17 December 2023 / Revised: 17 January 2024 / Accepted: 17 January 2024

Probiotics And Prebiotics In Intestinal Health And Disease: From Biology To The Clinic

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Probiotics, called live microorganisms, have been shown to improve or restore the microbiota in the gut, which in turn is associated with improved health. Probiotics are considered the equivalent of modern medicine, and they can treat or prevent a variety of diseases in children and adults (eg, colorectal and cardiovascular diseases in infants, respiratory infections and cancer in adults). Since the early 2000s, probiotic-based fermented foods have become popular due to claims of their health benefits. Fermented food is associated with the prevention of irritable bowel, lactose intolerance, gastritis and obesity, but also chronic diarrhoea, allergies, dermatitis and bacterial and viral infections, all of which are an unhealthy lifestyle. Recent and ongoing developments in the microbiome/microrobot have given us new research directions for probes. The new types, mechanisms and applications that have been studied so far and those that are currently being studied have great potential to change the scientific understanding of nutritional applications of probiotics and human health care. The expansion of fields related to the study of microorganisms and the involvement of probiotics in their improvement heralds an era of significant change. A growing array of candidate organisms is emerging that can address new data-driven microbial populations and host targets. Within probiotics, new varieties of microbiome modulating interventions are being developed, including probiotics, symbiotics, postbiotics, microbial communities, living biomedical products and genetically modified organisms, with interest in polyphenols, fiber and fermented foods to ensure human health. . This manuscript aims to analyze recent, emerging and projected trends in probes (sources, drugs, mechanisms of action, diseases, complications and risks of probes) and to generate perspectives on developments in the relevant field.

One of the looming problems of the 21st century is the need to feed a growing human population with ever-increasing natural resources. According to the literature [1], the role of balanced nutrition (aimed at protecting human health) is the main interest of the scientific community, and many studies have shown a reduction in the risk of certain diseases. By consuming certain protein-based foods. For this reason, research has been registered within research aimed at producing new natural products and creating new products, which enable real innovation in the food sector, as well as creating new market niches related to performance. Products. Gut development, energy metabolism, nutrient absorption and the immune system are all processes influenced by the gut microbiota, as well as our microbiome (the billions of microorganisms that form a complex ecosystem in our gastrointestinal tract) [2]. Recent and ongoing research in microbiology opens up new research fronts for investigational drugs, and clinical research on the heart muscle leads to new discoveries about their effects on human health. This new line of research will also allow researchers to make new discoveries about probiotic-based consumer products, their mechanisms of action in health, their nutritional uses and new investigational drugs. According to [3], new changes are emerging in human health due to the expansion of the field of interventions related to microbes and microbiota. In recent years, personalized nutrition (nutrients and nutraceuticals) and precision medicine have also begun to influence the use of probiotics, with increasing interest in altering microbial signatures of health and disease. Nutrition is concerned with identifying individual genetic changes that contribute to the body’s unwanted reactions when we consume certain foods. Our genetic activity, i.e. increase, decrease or inhibit the activity of genes.

Microorganisms live in and on us in symbiotic relationships, and it is estimated that almost 95% of these microorganisms are found in our intestines (mainly the large intestine), while the stomach and small intestine are relatively colonized. With advances in microbiology and genetic sequencing technology, the medical and pharmaceutical industries, the food industry, and the scientific community are beginning to better understand the role of these microorganisms and the metabolites they produce. Since these discoveries, the terms microflora and microbe have been widely used in the aforementioned groups [4].

Eden’s Synbiotic Supplement — The Ultimate Supplement For Gut Health

According to [4], microbiota is defined as a group of microorganisms present in defined environments and including human tissues (skin, lungs, oral mucosa, urinary tract, gastrointestinal tract), bacteria, fungi, viruses and fungi. channel). A microbiome can be defined as a microbe (and its genes) living in a specific environment. It is considered a “living ecosystem”. The gut microbiota is an important participant in the two-way communication between the gut and the brain, which is described as the microbiota-gut-brain axis [5].

The word “probiotic” has its roots in ancient Greek, meaning “life”. The authors of [6] postulate that Ferdinand Wergin may have coined the term “probiotic” in his 1954 article (“Antibiotic Resistance”), where he compared the toxic effects of antibiotics and other antibacterial agents on the gut microbiota. Beneficial effects of some beneficial bacteria [7]. Subsequently, the term “probiotic” was coined by Lilly and Stewell in 1965, who described them as factors secreted by one microorganism that promote the growth of another [8]. Parker [9] in 1974 redefined the term as “organisms and substances that contribute to the balance of intestinal microbes” and in 1989 Fuller [10] described the existence of live cultures used in food fermentation, opening the modern era of investigation. , used as additives to food products, antimicrobial agents are used in the form of dietary supplements, ointments and beauty products (gels, soaps, etc.). Specifically, he referred to probiotics as “live microbial feed supplements” that are beneficial to the host animal [9]. On the other hand, in 1998 Ref. [11] suggested that we need to use appropriate amount of probiotic strain to achieve beneficial effects. Currently, the most widely accepted scientific definition of probiotics, drawn up by the FAO (Food and Agriculture Organization of the United Nations) and the World Health Organization (WHO) in 2002, is “live microorganisms which, when administered in sufficient quantities, A. provide health benefits to the host” [12]. This is the definition